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ea0081p340 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Excellent disease control in Berardinelli Seip type 1 patient through dietary therapy alone: only an exception?

Cecchetti Carolina , Belardinelli Elisabetta , Dionese Paola , Teglia Rita , Di Cintio Ilaria , D'apice Maria Rosaria , Pagotto Uberto , Gambineri Alessandra

Background and Objective: Severe metabolic complications generally manifest at an early age in Berardinelli Seip congenital lipodystrophy (BSCL) and their management is especially challenging, often requiring prompt pharmacological treatment with insulin-sensitizers, lipid lowering drugs, insulin and eventually metreleptin. Nutritional intervention with low lipid personalized diets is considered by experts a fundamental tool in handling the disease when associated with ...

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ea0081p193 | Reproductive and Developmental Endocrinology | ECE2022

Efficacy of very low calorie ketogenic diet in obese PCOS: a randomized controlled study

Pandurevic Srdjan , Dionese Paola , Mancini Ilaria , Mitselman Dmitri , Magagnoli Matteo , Teglia Rita , Gazineo Domenica , Godino Lea , Fanelli Flaminia , Cristina Meriggiola Maria , Pagotto Uberto , Gambineri Alessandra

Background: Very low-calorie ketogenic diet (VLCKD) was shown to be effective in reducing weight and insulin resistance (IR) in obese patients. Considering that IR is very common in women with polycystic ovary syndrome (PCOS), and that IR worsens hyperandrogenism, ovulatory disfunction, and body fat accumulation, conceivably VLCKD could alleviate PCOS manifestations in the obese phenotype.Objective: This study compared the effects of a commercial VLCKD (...

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Endocrine Abstracts

Excellent disease control in Berardinelli Seip type 1 patient through dietary therapy alone: only an exception?

Efficacy of very low calorie ketogenic diet in obese PCOS: a randomized controlled study

BiosciAbstracts